【原】195523-86-5，H2N-WNRQLYPEWTEAQRLD-OH， H2N-Trp-Asn-Arg-Gln-Leu-Tyr-Pro-Glu-Trp-Thr-Glu-Ala-Gln-Arg-Leu-Asp-COOH

Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.

特异性高荧光FRET底物用于测定caspase-1 (ICE)和caspase-1样酶活性。在P1 Asp残基上切割Mca-YVADAPK(Dnp)，在392 nm的发射波长下进行连续荧光检测。Caspase-3 (apopain, cppp -32)在该底物上仅弱活性。caspase-1和caspase-3都参与细胞凋亡。肾ACE 2的特异性底物。

编号: 180265

中文名称: 褪黑素Melanocyte Protein PMEL 17 (44-59) (human, bovi

英文名: Melanocyte Protein PMEL 17 (44-59) (human, bovine,

CAS号: 195523-86-5

单字母: H2N-WNRQLYPEWTEAQRLD-OH

三字母: H2N-Trp-Asn-Arg-Gln-Leu-Tyr-Pro-Glu-Trp-Thr-Glu-Ala-Gln-Arg-Leu-Asp-COOH

氨基酸个数: 16

分子式: C95H137N27O28

平均分子量: 2105.27

精确分子量: 2104.01

等电点(PI): 6.58

pH=7.0时的净电荷数: -0.02

酸性基团个数: -1

碱性基团个数: 亲水

平均亲水性: 0.06

疏水性值: -1.6

来源: 人工化学合成，仅限科学研究使用，不得用于人体。

纯度: 95%、98%

盐体系: 可选TFA、HAc、HCl或其它

储存条件: 负80℃至负20℃

标签: 酶底物肽    促黑激素    癌症研究肽